ea0038p230 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2015
Ramamoorthy Thanuja Gali
, Allen Tiffany-Jayne
, Davies Alison
, Harno Erika
, Sefton Charlotte
, Wray Jonathan
, Murgatroyd Christopher
, White Anne
Background and objective: The prevalence of obesity is increasing worldwide and it is known that intra-uterine experience can program metabolic disorders. The hypothalamic appetite regulatory system is a key target of developmental programming by maternal nutrition. Therefore, the aim of this study was to investigate the effects of maternal overnutrition on the expression of hypothalamic genes controlling energy homeostasis.Research design: Eight week ol...